Matthew S. Karafin, MD

Assistant Professor of Pathology
Assistant Director of Transfusion Services, Dynacare Laboratories
Associate Medical Director, Medical Sciences Institute, BloodCenter of Wisconsin
Junior Investigator, Blood Research Institute, BloodCenter of Wisconsin

Matthew S. Karafin, MD

Matthew S. Karafin, MD


Dr. Karafin’s major responsibilities include Transfusion service work and instruction of medical students, residents, and fellows in general pathology and Transfusion Medicine. He oversees the Blood Bank and Therapeutic apheresis services for Froedtert Hospital/Medical College of Wisconsin and also directly supervises pathology residents on their coagulation rotations.

Research Interests
  • Red cell alloimmunization
  • Transfusion Reactions
  • Sickle cell disease
  • Immunohematology, molecular methods
Professional Background
  • Fellow, Transfusion Medicine, The Johns Hopkins Hospital, Baltimore, MD (2010-2011)
  • Resident, AP/CP, The Johns Hopkins Hospital, Baltimore, MD (2007-2012)
Educational Background
  • MD, The University of Iowa, Iowa City, IA (2007)
  • BA (Biology), Grinnell College, Grinnell, IA (2000)
Board Certifications
  • Anatomic and Clinical Pathology
  • Transfusion Medicine (Pathology)


1. M Karafin, RS Shirey, PM Ness, KE King. (2012). Antigen matched red cell transfusions for patients with sickle cell disease at The Johns Hopkins Hospital. Immunohematology. 28(1): 3-6.
2. M Karafin, S Stramer. (2012). The scientific method at work: Xenotropic murine leukemia virus-related virus is neither a cause of chronic fatigue syndrome nor a threat to the blood supply. Transfusion. 52(2): 222-5.
3. M Karafin, A Fuller, WJ Savage, KE King, PM Ness, AAR Tobian. (2012). The impact of apheresis platelet manipulation on corrected count increment. Transfusion. 52(6): 1221-7.
4. M Karafin, L Blagg, AAR Tobian, KE King, PM Ness, WJ Savage. (2012). ABO antibody titers are not predictive of hemolytic reactions due to plasma-incompatible platelet transfusions. Transfusion. 52 (10): 2087-93.
5. M Karafin, RS Shirey, J Keefer, PM Ness, KE King. (2012). A case study of a child with chronic hemolytic anemia due to a Donath-Landsteiner positive, IgM anti-I autoantibody. Pediatr Blood Cancer. 59(5): 953-5.
6. M Karafin, BH Shaz, CD Hillyer. (2013). Principles of Plasma Transfusion: Plasma, cryoprecipitate, albumin, and immunoglobulins. In: Hematology: Basic Principles and Practice (6th Ed.). Pg 1683-1694. (Invited review; book chapter 116).
7. M Karafin, CD Hillyer. (2013). Plasma Products. In: Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects (2th Ed.). Pg 209-219. (Invited review; book chapter 32).
8. M Karafin, BH Shaz. (2013). Human immunoglobulin preparations. In: Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects (2th Ed.). Pg 243-255. (Invited review; book chapter 37).
9. M Karafin, BH Shaz. (2013). Rh immune globulin. In: Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects (2th Ed.). Pg 255-259. (Invited review; book chapter 38).


Curriculum Vitae

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